N-DESMETHYL GLEEVEC
N-{4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}-4-(piperazin-1-ylmethyl)benzamide
CAS: 404844-02-6
Molecular Formula: C28H29N7O
N-DESMETHYL GLEEVEC - Names and Identifiers
| Name | N-{4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}-4-(piperazin-1-ylmethyl)benzamide |
| Synonyms | CGP-74588 STI 509-00 Norimatinib N-Desmethyl gleevec N-Desmethyl Imatinib IMATINIB METABOLITE N-DESMETHYL IMATINIB (N-DESMETHYL IMATINIB) N-{4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}-4-(piperazin-1-ylmethyl)benzamide N-{4-Methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}-4-(piperazin-1-ylmethyl)benzamide N-[4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-(1-piperazinylmethyl)-benzamide Benzamide,N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-(1-piperazinylmethyl)- |
| CAS | 404844-02-6 |
| EINECS | 1592732-453-0 |
| InChI | InChI=1/C28H29N7O/c1-20-4-9-24(17-26(20)34-28-31-12-10-25(33-28)23-3-2-11-30-18-23)32-27(36)22-7-5-21(6-8-22)19-35-15-13-29-14-16-35/h2-12,17-18,29H,13-16,19H2,1H3,(H,32,36)(H,31,33,34) |
N-DESMETHYL GLEEVEC - Physico-chemical Properties
| Molecular Formula | C28H29N7O |
| Molar Mass | 479.58 |
| Density | 1.268±0.06 g/cm3(Predicted) |
| Melting Point | 99-101°C |
| pKa | 13.28±0.70(Predicted) |
| Storage Condition | -20°C Freezer |
| Refractive Index | 1.676 |
N-DESMETHYL GLEEVEC - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| HS Code | 29339900 |
N-DESMETHYL GLEEVEC - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.085 ml | 10.426 ml | 20.852 ml |
| 5 mM | 0.417 ml | 2.085 ml | 4.17 ml |
| 10 mM | 0.209 ml | 1.043 ml | 2.085 ml |
| 5 mM | 0.042 ml | 0.209 ml | 0.417 ml |
Last Update：2024-01-02 23:10:35
N-DESMETHYL GLEEVEC - Reference Information
| use | N-desmethylimatinib is a heterocyclic derivative and can be used as a pharmaceutical intermediate. |
| biological activity | N-Desmethyl imatinib (Norimatinib) is a metabolite of Imatinib (HY-15463). Imatinib is a multi-target inhibitor of targeted v-Abl, c-Kit and PDGFR. |
Last Update：2024-04-09 21:49:45
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Spot supply
Product Name: Imatinib Impurity 6（Imatinib EP Impurity C） Visit Supplier Webpage Request for quotationCAS: 404844-02-6
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: N-Desmethyl Imatinib Visit Supplier Webpage Request for quotation
CAS: 404844-02-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 404844-02-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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